What are Essentials?

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USANA's foundation products are the ESSENTIALS^TM--the advanced nutritional products that everyone needs to take every day. They are designed to provide optimal nutritional support. The ESSENTIALS for adults are a combination of two products packaged as one:

• MEGA ANTIOXIDANT, a comprehensive formula of high-potency vitamins, antioxidants, and other important nutrients that every adult needs every day for efficient cellular metabolism and to counteract the damaging effects of free radicals.
• CHELATED MINERAL, a full-spectrum blend of essential minerals and trace elements in a balanced, highly bioavailable formulation. When taken together with MEGA ANTIOXIDANT, these supplements complete the nutritional foundation for every adult.

To maintain optimal health, we need a variety of vitamins, minerals, bioflavonoids, and other micronutrients. A healthy, diverse, balanced diet provides the foundation for good micronutrition. However, with today's lifestyle, it's impractical to obtain an optimal dose of all these nutrients. Furthermore, our diets are often far from balanced. As illustrated in the previous section, most people don't obtain even the minimal amounts of micronutrients needed to adequately support health, let alone the amounts needed to function at an optimal level.

USANA understands the importance of providing the right ingredients--in the correct amounts, in the right balance, and in the proper forms. USANA created the ESSENTIALS to provide the essential micronutrients that everyone needs every day.

THE RIGHT INGREDIENTS
The "essential" vitamins and minerals, as defined by government agencies and nutrition experts, are those that are needed for metabolic function, but are not manufactured by our bodies. We must obtain these ingredients from outside sources, and thus they are an "essential" part of our diets. These same experts have defined recommended Daily Values (DV) for those ingredients where a clearly defined deficiency disease or symptom has been observed.

USANA has expanded the meaning of "essential" micronutrition to include more than just those with an established DV. A variety of additional nutrients are important to maintain optimal health. The ESSENTIALS also contain trace minerals, mixed carotenoids, bioflavonoids, and other phytochemicals and antioxidants to provide a full arsenal of compounds to help protect against the daily bombardment of free radicals.

The newest ingredient in the ESSENTIALS for adults, USANA's patented Olivol^TM--The Heart of the Olive^TM-- is an extract from the fruit of the olive that contains phenolic antioxidants not found anywhere else in nature. The addition of this new, unique ingredient containing olive-specific phenolic antioxidants complements the already diverse selection of other antioxidants in the ESSENTIALS. The benefits of olive fruit and olive oil consumption are extensive, but until USANA added this extract to the ESSENTIALS, no commercial source of these phenolic antioxidants had been readily available.

THE CORRECT AMOUNTS
The established recommended Daily Values for vitamins and minerals were developed to show the minimum amount of those nutrients needed to avoid deficiency diseases. They do not tell you how much is needed to enhance your health. The ESSENTIALS are formulated to do more than just prevent deficiency diseases. The nutrients in the ESSENTIALS are set at levels to maintain optimal health and energy levels, based on the latest scientific data.

BALANCED FORMULAS
USANA reviews all the available scientific literature to ensure that the micronutrients present in our ESSENTIALS formulas are balanced to work together. While much is still not known about all the interactions that occur with nutrients in our bodies, USANA continues to keep abreast of the latest research to ensure up-to-date formulations.

THE OPTIMUM FORM
To be useful, all nutrients must be high quality and bioavailable--in other words, in a form the body can absorb and use. USANA takes the extra steps needed to obtain the highest quality ingredients with dependable levels of potency. In addition, USANA imposes rigorous quality controls at every step of the manufacturing process, following pharmaceutical GMP guidelines.

Chelated Mineral Essentials

Top-rated daily mineral supplement for adults

Health Basics

• Provides the essential minerals in highly bioavailable forms at safe and effective dosages
• Supports long-term health and well-being with energy-supporting co-enzymes*
• Supports healthy vision*
• Helps convert carbohydrates, fats, and proteins into energy*
• Supports bone, joint, and dental health*
• Designed to be taken with Mega Antioxidant for maximum benefit. Together, Mega

Antioxidant and Chelated Mineral compose the USANA Essentials^TM for adults.

Chelated Mineral Difference

• Formulated without iron

Minerals and trace elements represent less than one-half

of one percent of the total nutrients we consume every

day. Yet, without them our bodies would be unable to

efficiently use the carbohydrates, proteins, and fats in our

diet. Many vitamins and enzymes need a mineral co-factor

to function properly. The Chelated Mineral supplement

is a carefully formulated balance of essential minerals

and ultra trace minerals sourced from the highest quality

suppliers in forms readily absorbed by the body.*

Zinc

A component of hundreds of enzymes, zinc is involved in

carbohydrate, fat, and protein metabolism, as well as DNA

and RNA replication. Zinc functions as an antioxidant, aids in

retaining healthy bone structure development, healthy immune

function, and healthy vision, and supports normal fetal growth.1,2 *

Selenium

Selenium is an essential component of the glutathione

peroxidase antioxidant system, which helps combat the effects

of free radicals and plays an important role in thyroid hormone

metabolism.3 Selenium has also been shown to help support a

healthy immune system.4 In addition, many studies have shown

that selenium is important for retaining prostate health.5*

Magnesium

Magnesium is essential for the formation and maintenance

of healthy bones and teeth, which is where 70 percent of the

body's magnesium is found.6 It is involved in the metabolism of

carbohydrates and amino acids and plays an important role in

neuromuscular contractions. It is also an activator of hundreds of

enzymes essential to life.*

Chromium

Today's poor diets and unhealthy lifestyles often put stress on

the body's blood glucose control mechanisms. Chromium is an

important component of the glucose tolerance factor (GTF),

which helps retain healthy glucose metabolism, provided it is

healthy to begin with.7 Healthy insulin and glucose levels are

beneficial for weight management and sustained energy levels

throughout the day.*

Iodine

Iodine is a crucial component in the production of thyroid

hormones, which regulate metabolism, growth, reproduction,

and the synthesis of protein. Supplemental iodine is especially

important for people on a vegetarian diet, those who avoid

seafood, or those who must restrict their salt intake.*

Copper

Copper is a critical component of the enzyme superoxide

dismutase (SOD), is an important antioxidant in cell cytoplasm,

and acts as a catalyst in the formation of hemoglobin.8,9 Copper

is also essential for collagen synthesis.10 *

Manganese

Manganese is an important co-factor in the production of

glycosaminoglycans, compounds that make up connective

tissues, bones, arteries, and other organs.1

Manganese is an activator of numerous enzymes, and

supplementation with manganese can enhance the SOD enzyme

system to increase antioxidant activity.11,12*

Vanadium

Vanadium helps support healthy serum glucose levels, provided

they are healthy to begin with, and may also help retain healthy

thyroid function.13,14 *

References

1. Saltman PD, Strause LG. J Am Coll Nutr 1993;12:384-89.

2. Simmer K, et al. Eur J Clin Nutr 1991;45:139-44.

3. Holben DH, Smith AM. Diet Assoc 1999;99:836-43.

4. Baum MK. Proc First Inter Bio-Minerals Symposium. April 19-20, 2001.

5. Blumenfeld AJ, et al. Can J Urol 2000;7:927-35.

6. Ilich JZ, Kerstetter JE. J Am Coll Nutr 2000;19:715-37.

7. Mertz W. J Nutr 1993;123(4):626-33.

8. Harris ED. Ann Rev Nutr 2000;20:291-310.

9. Turnland JR. Modern nutrition in health and disease. Baltimore: Williams & Wilkins; 1999.

10. Rucker RB, et al. Am J Clin Nutr 1998;67(5 Supp):996S-1002S.

11. Fleet JC. Biochemical and physiological aspects of human nutrition. Phildelphia: Saunders; 1998.

12. de Rosa G, et al. J Nutr 1980;110:795-804.

13. Nakai M, et al. Biol Pharm Bull 1995;18:719-25.

14. Yuan M, et al. Chung Hua I Hsueh Tsa Chih 1997;77:208-11.

Supplement Facts

Serving Size 1 Tablets

Amount per serving                            %DV*

Calcium (as Calcium Citrate And Carbonate )                        90 mg                                      10%

Magnesium (as Magnesium Citrate ,                                       100 mg                                    40%

Amino Acid Chelate )

Iodine (as potassium iodide)                                                    66 μg                                      45%

Zinc (as zinc citrate )                                                               5 mg                                        35%

Selenium (as L-selenomethionine                                              33 μg                                      45%

and Amino Acid Complex)

Copper (as Copper Gluconate )                                              0.66 mg                                   35%

Manganese (as Manganese Gluconate )                                   1.3 mg                                     70%

Chromium (as chromium Polynic otinate and                            80 μg                                      70%

picolinate **)

Molybdenum (as Molybdenum Citrate )                                   16.7 μg                                   25%

Silicon (as Silicon Amino Acid Complex)                                 1 mg                                        †

Vanadium (as Vanadium citrate )                                              10 μg                                      †

Sea Salt                                                                                   1 mg                                        †

* Percent Daily Values are based on a 2,000 calorie diet.

† Daily Value not established.

** Licensed under U.S. Patent 4,315,927.

Directions: Take one  tablets Twice daily , preferably with food.

Other Ingredients: Microcrystaline Celulose,Pregelatinized Starch,

Croscarmelose Sodium, Colloidal Sillicon Dioxide, Ascorbyl Palmitate.

laboratory tested, quality guaranteed. meets usp specifications

for potency, uniformity, and disintegration, where applicable.

AO Pro Essentials

Top-rated daily vitamin and antioxidant supplement for adults

Health Basics

• Offers an unparalleled range of antioxidant nutrients for protection against oxidative stress,

the cell-damaging process that results from environmental pollutants and natural aging*

• May help reduce the visual effects of normal, age-related decline*
• Supports healthy immune function*
• Designed to be taken with Chelated Mineral for maximum benefit. Together,

Antioxidant Pro and Chelated Mineral compose the USANA Essentials^TM for adults.

Daily stress and environmental pollutants bombard us with increasing

levels of potentially damaging, highly reactive molecules called

free radicals. Diets high in processed foods and low in whole,

unrefined foods have increased the need for vitamins and antioxidant

supplementation.Antioxidant Pro offers advanced levels of highquality,

highly bioavailable vitamins and antioxidants to meet this

increased need.Antioxidant Pro also offers nutritional support

for retaining sound cardiovascular function, healthy vision, a sound

immune system, and efficient energy metabolism.*

Vitamin E-The Premier Antioxidant

Vitamin E is a family of essential fat soluble nutrients (tocopherols and

tocotrienols) that act as powerful antioxidants. D-alpha tocopherol is the

natural form shown to have the greatest nutritional and biological value.

Vitamin E plays a critical role in protecting LDL and cell membranes from

oxidation, and it works synergistically with other antioxidants to combat

free-radical damage.3 Emerging science has shown that other tocopherols

also provide important biological activities and therapeutic benefits.4 These

mixed tocopherols help leverage the health benefits of alpha tocopherol with

other vitamin E compounds to provide a broad spectrum of antioxidant

protection. In addition to D-alpha tocopherol, USANA's advanced formula

offers a full range of these natural mixed tocopherols to provide you with

additional antioxidant support.*

USANA'S Unique Poly C® Vitamin C Complex

USANA's Poly C® is a complex of mineral ascorbates that helps to prolong

vitamin C activity in the body. Vitamin C is the master water-soluble

antioxidant, providing antioxidant activity.4*

Mixed Carotenoids

USANA uses a mixture of carotenoids, providing a broad spectrum of

antioxidant protection. Beta carotene (provitamin A) promotes healthy skin,

a strong immune system, and helps maintain good vision.5-9*

Antioxidant pro includes the safe provitamin form of vitamin A, beta

carotene, which naturally converts into vitamin A only as needed, giving you

the benefits of vitamin A without the risk of toxicity.*

In addition, lutein and lycopene are carotenoid antioxidants involved in

protecting against free-radical damage in the eyes and other organs.10-12

Lutein selectively accumulates in tissues in the eye to help protect against

damaging UV radiation.13 Lycopene supports health maintenance for many

organs, including the lungs, skin, cervix, and prostate gland.10,11*

Coenzyme Q10

A potent antioxidant, coenzyme Q10 (CoQ10) is essential for energy

production in our cells.14 One of the most researched and well-accepted

nutrients for cardiovascular health, CoQ10 is especially important for a

strong cardiovascular system.15 The body's ability to synthesize or absorb

CoQ10 declines with age, but taking USANA's Antioxidant Pro can help

you maintain healthy levels of this important nutrient.*

Alpha Lipoic Acid

Alpha lipoic acid is a vitamin-like antioxidant that is both fat- and watersoluble.

In addition to acting as an antioxidant on its own, alpha lipoic acid

can increase or maintain levels of other antioxidant compounds, such as

glutathione and vitamin C.15,16*

Bioflavonoid Complex

Through our commitment to ongoing research, USANA has developed a

unique broad-spectrum bioflavonoid complex. Bioflavonoids are a diverse

group of naturally occurring plant compounds that exhibit a host of

biological activities, most notably their powerful antioxidant properties that

help complement, extend, and synergize the activities of other antioxidants.

In addition to synergistic activity from rutin, quercetin, and hesperidin, this

diverse complex provides green-tea, bilberry, pomegranate, and cinnamon

extracts to provide broad-spectrum antioxidant support to further enhance

and complement the effectiveness of Antioxidant Pro supplement.*

Complete Vitamin B Complex

Antioxidant Pro contains carefully proportioned B-complex vitamins,

which are fundamental to energy production, metabolism, growth, and

maintenance of normal homocysteine levels, provided they are normal to

begin with.*

The U.S. Centers for Disease Control has stated, "All women of

childbearing age in the United States who are capable of becoming pregnant

should consume at least 400 μg of folic acid per day for the purpose of

reducing their risk of having a pregnancy affected with spina bifida or other

neural tube defects."17 One daily dose of Antioxidant Pro contains 333

μg of folic acid.*

Vitamin B12 is necessary for the health of nerve cells, red blood cells, and

DNA, the genetic material in all cells.18 It has been generally accepted

that older adults are at greater risk of developing a vitamin B12 deficiency

than younger adults. However, new research suggests that the prevalence

of vitamin B12 deficiency in young adults may be greater than previously

thought, and those who do not take a supplement containing vitamin B12

are twice as likely to be vitamin B12 deficient as supplement users, regardless

of age group.19 Antioxidant Pro supplies advanced levels of vitamin B12 at

20 μg in one daily dose.

References

1. Caruso D, et al. Nutr Metab Cardiovasc 1999;9:102-7.

2. Visioli F, et al. Atherosclerosis 1995;117:23-32.

3. Engelen W, et al. Am J Clin Nutr 2000;72:1142-9.

4. Carr AC, et al. Cir Res 2000;87:349-54.

5. Eicker J, et al. Photochem Photobiol Sci 2003;2(6):655-9.

6. Semba RD. Clin Infect Dis 1994;19(3):489-99.

7. Semba RD. Proc Nutr Soc 1999;58(3):719-27.

8. Stephensen CB. Annu Rev Nutr 2001;21:167-92.

9. Age-Related Eye Disease Study Research Group. Arch Ophthalmol 2001;119(10):1417-36.

10. Guttenplan JB, et al. Cancer Lett 2001;164:1-6.

11. Rao AV, Agarwal S. J Am Coll Nutr 2000;19:563-9.

12. Seddon JM, et al. JAMA 1994;272:1413-20.

13. Beatty S, et al. Arch Biochem Biophys 2004;430(1):70-6.

14. Sinatra ST. The CoEnzyme Q10 phenomenon. New Canaan: Keats Pub; 1998.

15. Schneider D, Elstner EF. Antioxid Redox Signal 2000;2:327-33.

16. Packer L, et al. Adv Pharmacol 1997;38:79-101.

17. Rayburn WF, et al. J Am Cll Nutr 1996;15(2):121-5.

18. Herbert V. Intl Life Sci Inst Press 1996.

19. Tucker KL et, al. Am J Clin Nutr 2000; 71:514-22.

Supplement Facts

Serving Size: 1 Tablets

Amount per serving                            %DV*

Vitamin A(asBeta Carotene)                                                             1666 IU                                   35%

Vitamin C (asCalcium, Potassium, Magnesium,                                  333 mg                                    560%

& ZincAscorbates)

Vitamin D3 (asCholecalciferol)                                                           133 IU                                     35%

Vitamin E(asD-Alpha Tocopheryl Succinate)                                      133 IU                                     440%

Thiamin (asThiamin HCl)                                                                    9 mg                                        660%

Riboflavin                                                                                           9 mg                                        530%

Niacin (asNiacin andNiacinamide)                                                      13.3 mg                                   70%

Vitamin B6 (asPyridoxine HCl)                                                           9 mg                                        450%

Folate (asFolicAcid)                                                                            333 μg                                    80%

Vitamin B12 (asCyanocobalamin)                                                        20 μg                                      330%

Biotin                                                                                                  100 μg                                    35%

PantothenicAcid(asD-Calcium Pantothenate)                                      30 mg                                     300%

BioflavonoidComplex [Rutin, Quercetin, Hesperidin                            59 mg                                      †

(Citrus spp. L., fruit)

Inositol                                                                                               50 mg                                       †

Choline Bitartrate                                                                                33.3 mg                                   †

N-Acetyl L-Cysteine                                                                           21.7 mg                                   †

Bromelain                                                                                           16.7 mg                                    †

Alpha LipoicAcid                                                                                5 mg                                        †

Coenzyme Q10                                                                                  4 mg                                         †

Lutein (Tagetes erecta L., flower)                                                      200 μg                                     †

Lycopene                                                                                           350 μg                                     †

*Percent Daily Values are based on a 2,000 calorie diet. †Daily Value not established.

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